DSR-M Dissolution Sampling Robot

The dissolution sampling robot with media refilling and dilution option.

The DSR-M dissolution sampling robot of Pharmatest is designed specifically for the sample transfer and sample processing from a six to twelve vessel dissolution bath. This unique versatile instrument allows samples to be collected over very short time intervals. The DSR-M can be equipped to collect, dilute or process samples for following UV-Visible or HPLC measurements. It can also be used for dissolution medium replenishment to conform to USP/EP volume loss rules.

To offer the highest volume precision, between six and thirteen piston pumps are used for sample removal and media refilling (optional), one dedicated pump for each channel. No time consuming pump calibration is needed. The advanced design of the system means that it is always ready for operation. The pumps are integrated into the DSR-M as a compact CAT-M pump module. The sample preparation station, Z-arm and needle, can be used to dispense into septa sealed HPLC vials or dilute the samples for later UV/VIS analysis. Keeping the samples in sealed vials helps to avoid evaporation, especially if sustained release samples are tested.

If dilution of sampled media is required the DSR-M will use one of the two racks to collect the samples from the dissolution vessels and the second one will hold empty vials into which the diluted media will be dispensed. When sampling is finished the DSR-M will start to dilute. It will take the volume which needs to be diluted from the sampled media dispense it into the empty vials and add the diluent while mixing both using air.